Endocrine Abstracts

Introduction: Type 2 diabetes is one of the main risk factors for severe COVID 19 infection. Inadequate glycemic control is related to high inflammation, hypercoagulability, and mortality in COVID-19 patients. Glucose lowering medications commonly used to treat diabetes mellitus (DM) might have effects on COVID 19 pathogenesis. Overall, evidence is conflicting as to which glucose-lowering drugs are associated with the most favourable outcomes in patients with COVID-19. The aim...

Introduction: IDegLira is the first fixed ratio combination of a basal insulin degludec and a glucagon-like peptide-receptor analogue liraglutide. These combination producereduction in glycated hemoglobin A1c (HbA1c) and help to mitigate the weight gain. The aim of this study was to evaluate relationship between change in glycemic parameters and body weight in patients who began therapy with IDegLira.Patients and Methods: Retrospective study included 86 ...

Bone metabolism disorders in hemodialysed patients (HD) involve several humoral factors, of which PTH plays the central role. Leptin is a protein hormon secreted by the adipocytes and related to malnutrition, anemia and bone metabolism disorders in chronic kidney disease patients. The aim of the study was to was to evaluate serum leptin levels and bone metabolism in chronic HD patients depending on body mass index (BMI). This cross section study included 93 HD patients distrib...

Sixteen percent of parathyroid adenomas can be situated in an ectopic location. Ectopic parathyroid glands result from aberrant migration during early stages of development, and lack of successful identification may lead to lack of success in parathyroid surgery. These glands are most frequently found in the anterior mediastinum, in association with the thymus or the thyroid gland. Ectopic parathyroid glands are a major cause of persistent and recurrent hyperparathyroidism.</p...

Introduction: Increased levels of high-sensitivity C-reactive protein (hs-CRP) and interleukin 6 (IL-6) accelerates atherosclerosis and occurrence of cardiovascular complications in patients with type 2 diabetes (T2D). Intima-media thickness (IMT) is a surrogate marker of atherosclerosis in patients with T2D.Aim: The aim of the study was to evaluate the significance of determining inflammatory markers IL-6, hs-CRP and IMT, as atherosclerosis markers, dur...

Introduction: Clinical assessment of atherosclerotic complications in type 2 diabetes mellitus (DM) was diverted to the detection of subclinical form of atherosclerosis using the non-invasive diagnostic methods. Surrogate markers of subclinical atherosclerosis are carotid intima-media thickness (IMT) and albuminuria. The aim of this study was to analyze a relationship between the presence of albuminuria and carotid IMT in patients with type 2 DM and silent ischemia.<p clas...

IntroductionDiabetes mellitus (DM) is considered as equivalent to cardiovascular disease (CVD), so the intensive control of all risk factors for CVD in patients with DM is recommended. Risk factors for CVD include: dyslipidemia, hypertension, smoking, family history of CVD and albuminuria. In addition to being a sensitive and reliable marker for evaluation of kidney function, research suggests that cystatin C may be a useful predictor for the detection a...

AimDiabetic cardiomyopathy (DC) is congestive heart failure developed in diabetic patients, without coronary, hypertensive, valvular nor myocardial alcoholic disease. Aim of this stady was to confirm if presence of diabetic autonomic neuropathy (DAN) is correlating with development of DC in patients with diabetes.MethodsWe have evaluated 90 examinees: 30 of them with diabetes type 1(T1D), 30 with diabetes typ...